IGNYT
Scientifically Proven GLP-1 & GIP Receptor Agonist Powered by Patented Bioactive Peptides
CLINICAL TRIALS & PUBLISHED STUDIES
Iron Deficiency Anemia: Ferritin & Hemoglobin Levels Following ProGo® Supplementation vs. Whey Protein
n = 48 · Placebo-controlled vs. whey protein isolate · 6 weeks · 16g/day+140% ferritin (restored to normal); +14% hemoglobin vs. +2% in whey group (p<0.05). Basis for 6 FDA structure/function claims & Health Canada qualified claims.
Weight Management & Metabolic Biomarkers: Randomised Placebo-Controlled Study on BMI in Overweight Adults
Overweight subjects · Placebo-controlled vs. WPI · 42 days · 16g/day−5.9% BMI (p<0.05); significant changes in 4 metabolism-relevant serum biomarkers; consistent 3–6% reduction in fasting blood glucose.
Investigating the Efficacy of 18-Week Salmon Protein Hydrolysate Supplementation on Metabolic Inflammation, Well-Being & Cosmetic Outcomes
n = 20 · Open-label, single-arm · 128 days · 4g/day · KGK Science Inc.+10.24% perceived energy (women +14.55%); −9% oxidative stress; HMOX1 ↑4.09×; FTH1 ↑3.77×; skin/hair/nail +24% (women +34.5%); IL-5, IL-8 & CRP reduced.
A Randomized, Double-Blinded Cross-Over Study Comparing Increase in Blood Leucine Levels after Ingestion of Hydrolyzed Salmon and Whey Proteins in Healthy Young Men
n = 6 · Randomised double-blind crossover · 16g doses · Norwegian School of Sport SciencesProGo® reached peak blood leucine 15 min faster than WPC-80; rapid aminoacidemia; comparable insulin response.
Initial Exploration of the In Vitro Activation of GLP-1 and GIP Receptors and Pancreatic Islet Cell Protection by Salmon-Derived Bioactive Peptides
In vitro · Currie C. et al. · Hofseth BioCare
Smallest ProGo® peptide fraction activates GLP-1 & GIP receptors; pancreatic islet cell protection; DPP-IV inhibition; improved glucose uptake into muscle.
Soluble Protein Hydrolysate Ameliorates Gastrointestinal Inflammation and Injury in TNBS-Induced Colitis in Mice
Mouse model of colitis · Wei J. et al. · Stanford University & Hofseth BioCare
ProGo® significantly reduced colon tissue injury, inflammatory cell infiltrates & oxidative stress. HMOX1 upregulation confirmed. Led by Dr. Karl Sylvester MD, Stanford.
Glucoregulatory Bioactivity of ProGo® Peptides: DPP-IV Inhibition and Glucose Uptake in Muscle Cells
In vitro · Hofseth BioCare
ProGo® peptides demonstrated potent DPP-IV inhibition and improved glucose uptake into muscle — augmenting insulin action, boosting satiety, reducing metabolic disease risk factors.
Antioxidant Gene Expression: ProGo® Upregulates 16 Oxidative Protective Genes Including FTH1, HMOX1 & ALOX12
Human cell lines · HBC & Stanford University
ProGo® upregulated 16 oxidative protective genes and downregulated 9 oxidative stress genes. FTH1, HMOX1 & ALOX12 showed notable fold-change supporting observed clinical benefits.
